The Protein database is a collection of sequences from several sources including translations from annotated coding regions in GenBank RefSeq and TPA as well as records from SwissProt PIR PRF and PDB. As these interactions are of a critical nature in many important cellular functions and their dysregulation is causal of disease the modulation of these binding.
Matrix Metalloproteinase Expression And Molecular Interaction Network Analysis In Gastric Cancer
The Human Cancer Proteome Project Cancer-HPP is an international initiative whose key objective is to decipher the human cancer proteome through a coordinated effort by cancer proteome researchers around the world.
Protein cancer database. Human Protein Reference Database. The Human Protein Atlas. Protein expression data is derived from antibody-based protein profiling using immunohistochemistry.
The workflow of RBPTD was showed as following. Cancer Gene Expression Database. The cancer tissue atlas contains gene expression data based on protein expression patterns in 216 different cancer samples representing the 20 most common forms of human cancer.
21 rows Databases for oncogenomic research are biological databases dedicated to cancer. The Network Data Exchange NDEx cBioPortal cBio Human Proteome Organization. Cancer gene expression database CGED -- a database for gene expression profiling with accompanying clinical information of human cancer tissues.
Therefore we developed a database named RBPTD to identify cancer-related RBPs in humans and systematically explore their functions and abnormalities by integrating different types of data including gene expression profiles prognosis data and. Targeting the central dogma. Protein sequences are the fundamental determinants of biological structure and function.
A total of 124 previously published transcriptome datasets were collected from Gene Expression Omnibus GEO and The Cancer Genome Atlas TCGA. Transcriptomes were compared to examine the expression. The goal is to map the entire human cancer proteome to disclose tumour biology leading to improved diagnostics and treatment of.
Cancer-related variations and conrresponding annotations can be queried through the web-interface using Protein IDs in the Ensembl IPI RefSeq and UniportSwiss-Prot databases. 22022018 Since then a series of cancer proteome databases have been established. As a member of the wwPDB the RCSB PDB curates and annotates PDB data.
The data is presented as pathology-based annotation of protein. RBPTD is a database for identifying cancer-related RBPs in humans and systematically investigating their functions and abnormalities by integrating different types of data including gene expression profiles prognosis data and DNA copy number variation CNV among 28 cancers. The Pathology Atlas contains mRNA and protein expression data from 17 different forms of human cancer.
Correlation analyses based on mRNA expression levels of human genes in cancer tissue and the clinical outcome for almost 8000 cancer patients is presented in a gene-centric manner including more than 18000 Kaplan-Meier plots with high significance p0001. CanProVar is designed to store and display single amino acid alterations including both germline and somatic variations in the human proteome especially those related to the genesis or development of human cancer based on the published literatures. PED 5 and PCD 6 are both the databases of pancreatic cancer containing multi-dimensional data types pertaining to quantitative alterations.
For instance DBGC 4 collected DEPs focused on gastric cancer-related transcriptomic and proteomic data. Between 40000 and 200000 protein-protein interactions have been predicted to exist within the human interactome. Genomic status of proteins in the form of mutation.
Protein-protein interactions and cancer. Find comprehensive links to reliable information about genes their associated proteins and genetic mutations associated with cancer and related disorders. 13072021 This resource is powered by the Protein Data Bank archive-information about the 3D shapes of proteins nucleic acids and complex assemblies that helps students and researchers understand all aspects of biomedicine and agriculture from protein synthesis to health and disease.
HCMDB Human Cancer Metastasis Database is an integrated database designed to store and analyze large scale expression data of cancer metastasis. 10022016 This database comprises of crucial information of apoptosis proteins in the context of cancer.
Tumor Suppressor Gene Database Tsgene Home
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