Highly alkaline urine 8 can produce a false positive result. A diagnosis of proteinuria or excess protein in the urine may be alarming for cat owners but a plan can be made with your veterinarian for your cats long-term care and quality of life.
Proteinuria is a condition that is described as an excess of protein in the urine of the cat.
Protein in cat urine eclinpath. Interpreting the Numbers--Azotemia and Urine Specific Gravity - WSAVA2008 - VIN. Mixture of non-degenerate neutrophils and macrophages roughly 5050 but can vary from 2080 to 8020 with low numbers of small lymphocytes and mesothelial cells. On the Mod P we measure protein in urine and CSF with benzethonium chloride which precipitates the protein and increases the turbidity of the sample.
In this situation a urine proteincreatinine UPC ratio greater than 04 in a cat and 05 in a dog indicates there is significant protein loss through the kidneys and a diagnosis of primary kidney disease can be made. A positive SSA protein reaction with a negative or weak dipstick protein reaction in a dog or cat with a high index of suspicion for multiple myeloma is suggestive of the presence of free light chains in the urine. However bleeding or inflammation in the urinary system is a far more common cause of proteinuria.
This represents small protein particles those tiny enough to pass through the pores of the glomeruli the kidneys microscopic filtration units. The glomeruli prevent albumin and other larger protein particles from entering the urine. A diet change is often required to ensure your cats renal health.
If proteinuria is not due to inflammation or bleeding in the urinary system then it is more likely to be a sign of. Typically the cats urine contains a low quantity of proteins but if the proteins are in higher amounts the cat should be checked. Reactive lymphocytes or plasma cells may be seen.
If the proteinuria is significant does not fall into above circumstances then a urinalysis with sediment examination is. Total protein by refractometer. This is because the dipstick is less sensitive to free light chains of immunoglobulins but the SSA will precipitate these proteins.
These proteins are a very heterogenous group of over a thousand individual proteins with a variety of functions including maintenance of oncotic pressure transportation of substances coagulation etc. Normally there should be no protein in the urine. There are a few possible causes leading to an excessive release of.
In some situations it may even be a sign of kidney failure. Further investigation and treatment are recommended. The presence of protein in urine is called proteinuria.
At a concentration of 2400 mgdL the USG increased by 0002 to 0008 in pooled feline urine. 24042015 Cats can normally have a trace amount of protein in their urine. The protein test detects mainly albumin.
A decreasing linear relationship became evident when urine was spiked with 600 2400 mgdL but there was more individual cat variation leading to r 2 ranging from 026 to 048 for these glucose concentrations. This may indicate that the kidneys are not working properly. However a trace or 1 reaction is considered normal with a specific gravity greater than 1035.
The turbidity is proportional to the protein concentration. In addition to monitoring proteinuria and evaluating the response to therapy the UPC ratio can be used to determine the approximate survival time of the cat. Addition of 50-300 mgdL had random effects increase and decrease of USG of 0007 in individual cats with USG.
Physiologic prerenal proteinuria may result from excessive muscular exertion convulsions or excess protein ingestion. In this section we will cover the following. Relation of Survival Time and Urinary Protein Excretion in Cats with Renal Failure andor Hypertension The degree of proteinuria is predictive of the survival times in cats with CRF.
Many false positive protein tests occur especially with alkaline urine. Proteins account for a large amount of the dissolved substances in plasmaserum. This technique is very sensitive and can yield accurate results in samples with very low protein concentrations.
PROTEIN URIA IN DOGS Proteinuria is defined as the presence of excess protein in the urine. Creatinine is a substance that appears in the blood as the result of muscle activity and is excreted by the kidney at a constant rate. A small amount of protein normally is present in urine and may be detected in concentrated urine.
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